Document Type : Research Paper
Authors
Department of Computer Science and Engineering, Velagapudi Ramakrishna Siddhartha Engineering College, Vijayawada, India.
Abstract
Keywords
Introduction
An unknown viral pneumonia outbreak occurred in Wuhan's population in December 2019. In 2019, an ICTV (International Committee on Taxonomy of Virus) officially designated Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) as the cause of coronavirus illness 2019. (COVID19). Because of SARS-fast CoV-2's spread and high infectiousness, early screening, isolations, & treatment action for individuals caused by corona are critical. One of many coronaviruses, the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) virus is characterized by its single-stranded RNA genome and lack of segmentation (Zhou P et al., 2020). Open reading frame 1ab (ORF1ab), the 5′ untranslated region (UTR), the spike gene (S gene), the envelope gene (E gene), the membrane gene (M gene), the nucleocapsid gene (N gene), the 3′ UTR, and a number of unknown unstructured open reading frames are all found in the RNA genome (Qiang X L et al., 2020).
It is possible to undertake quantitative analysis using standard curves and real-time quantitative PCR (qRT-PCR). Fluorescent groups are included in PCR reaction systems, and the buildup of fluorescent signals is monitored in real-time. SARS-CoV-2 is diagnosed by qRT-PCR because of its high sensitivity and excellent specificity. 2–6 as of now, qRT-PCR is most often used to identify SARS-CoV-2.7–9 in throat or nose samples; other studies have also used serum or fecal or ocular secretions (Ou X et al., 2020). When analyzing SARS-CoV-2, reverse transcriptase (RT), PCR, & Taqman probes must be used. 3 In most cases, results are available within four to six hours. Due to their ability to minimize non-specific amplification, Taqman probes may reduce false-negative findings if the binding sites contain variations. Furthermore, since the targets for SARS-CoV-2 testing share similar gene segments with SARS-COV-2, FP (False Positive) findings used for further corona virus deceases are possible. This can be done by synchronizing the finding of many objective frequencies or by generating more accurate primers and probes for the virus's genetic material progression (Kailasam S et al., 2021).
A number of issues have arisen with qRT-PCR assays used for COVID-19 test, however. First and foremost, since RNA viruses are subject to mutation and recombination, the sensitivity of these tests may be reduced. Experiment settings and staff performance have a significant impact on the detection outcomes (Moore J H et al., 2020). It was stated in the clinic that a CT scan was positive but qRT-PCR results were negative. Consequently, several scientists and doctors feel that CT scan data and qRT-PCR results should be coupled to evaluate infection, therapy and outcome. Early detection, isolation, & treatment of COVID-19 are critical on this point, according to qRT-PCR tests against the virus (Alkhamis M A et al., 2020). Standardizing sample compilation, integrating multi-site and multi-species findings, tightly monitoring the excellence of reagent equipment, and enhancing laboratory excellence are all ways to increase the accuracy of SARS-CoV-2 testing in follow-up studies (Dhiman, G et al., 2021).
Portable equipment for SARSCoV-2 screening may be easily used and findings can be easily shown in this mini-review (Gerkin R C et al., 2020). For the most part, the assays described in this study use nucleic acid detection & antibody detection as their foundations. COVID-19 should be easier to diagnose with these new tests, which we hope to be published in the near future (Qiang X & Kou Z, 2019).
SARS-CoV-2 S and N proteins, for example, induce an organism's humoral immune response, which may lead to an antibody response. Early antibodies include IgM and subsequently IgA antibodies, which then progress to IgG antibodies (Guan W J et al., 2020). The concentration of IgG antibodies will continue to rise, while the concentration of IgM antibodies will go on to drop until it vanishes, and IgG antibodies will be there for a longer duration. Specific IgM & G antibodies are a pair that emerges sequentially and the alterations in both antibodies are linked (Saikumar K et al., 2022).
Due to the fact that viral load drops over the course of a week after the onset of symptoms, testing results are highly dependent on when samples are taken (Zhu N et al., 2020). Anti-IgG and anti-IgM antibodies may be detected depending on the seroconversion potential of the patient and normally appear one to two weeks after the onset of symptoms, although this might take longer in certain cases. PCR detection's sensitivity is going to be drastically degraded at this point. When COVID-19 was diagnosed by immunoassay, it was discovered that the IgG ratio grew over time from one week after symptoms began to emerge, whereas the method's susceptibility peaked and subsequently fell (Ruben J G et al., 2019). When developing COVID-19, it was discovered that IgM may be present sooner than IgG, therefore simultaneous testing of both may improve diagnosis accuracy. lateral flow assay (LFA) is a simple and rapid approach that does not need much training before it can be used. LFA's price and simplicity of use make it ideal for testing facilities with limited resources or hospital point-of-care (POC) scenarios. Half-strip LFA was used in COVID-19 detection by Grant and colleagues. An investigative casing to a wicking pad were used in the half-strip LFA, which may be used to pre-mix the sample and conjugate in a 96-well plate (Sifuentes-Rodríguez E & Palacios-Reyes D, 2020). As for the detection level, it stood at 0.65 ng/mL. More than 18 days after the beginning of the initial symptoms or in no symptoms patients, IgG antibody testing is particularly useful. It's not clear whether assessing IgA or M is similarly effective, but their findings suggest that doing so might lead to more false-positive outcomes without considerably enhancing diagnostic performance (Kouser, R.R et al., 2018). A total of 92.1 percent of all LFAs were able to identify IgG antibodies 14-25 days following the start of symptoms, but an IgG ELISA could only detect 89.5 percent. The sensitivity of LFAs for the detection of IgG antibodies was reported to be > 92.00 percent on 2–3 weeks after the first symptoms, whereas the sensitivity of ELISAs was 89.5 percent for the detection of IgG (Qian Z et al., 2015).
Electrochemical detection: Biosensors with high sensitivity, cheap cost, simplicity of use, and robustness may be used in clinical diagnostics since they have these properties. It is expected that electrochemical biosensors will play an essential role in clinical diagnostics & point-of-care (POC) recognition in the future. For nucleic acidic biosensors, super sandwich-type electrochemical biosensors offer a lot of promise in the diagnostic arena (Kumar K S et al., 2021).
When it comes to the electrochemical paper analysis device (ePAD), there are three different types: one that is used for the actual testing of COVID-19 and the other two that are used for countering. The S protein, which includes the RBD, is utilized to ensure that the COVID-19 antibody enters the functional ePAD examination segment. Analyze the electrochemical response using the SWV approach, which diminishes as immune complexes build. SWV. In a paper-based electrochemical technique for immunoglobulin detection, Yakoh et al. reported 100% sensitivity and 90% specificity. Data collection for epidemiological reporting & communication of test results with doctors may be smoothly integrated via telemedicine systems when mobile devices are used as testing equipment (V., Muthukumaran et al., 2021). Electrochemical detection of SARS-CoV-2 RNA utilizing calixarene-functionalized graphene oxide was developed by Zhao et al. 85.5 percent of the time with 200 copies/mL. That team created a diagnostic system called plug–and–play. The best thanks to tracking the covid-19 natural event are victimization information & visualization. COVID19 patterns are often conflicting, and when representations are accessible, this is often the case (Djomkam A L et al., 2020). Information visualization is allowing comprehension of the coronavirus epidemic with the toilet. Dashboards from Johns Hopkins University and the World Health Organization provide updates. Severe Acute Metabolic Syndrome (SAMS) has caused a widespread irruption of coronavirus in 2019.
COVID-19 Indian dataset
|
Training set |
Feature representation Algorithm |
Progressive hypothesis |
Normalized features |
COVID-19 Outbreak |
Total population |
Figure 1. Time series and Nonlinear ML block diagram
Human populations have been devastated by Coronavirus 2. It has been an unbroken way of reporting new cases and fatalities since its inception in China's metropolitan center town. What makes it further worse is the virus's virulence and, as yet, undiscovered method figure 1. The present task of accomplishment has been sluggish to multiply due to societal distance, resulting in a hurry to provide advanced, effective diagnostic tools in addition to treatments.
By using visualizations to map the coronavirus, data scientists and researchers are cooperating. Visual image approaches are assisting the general population in comprehending COVID-19 and implementing safety measures. The John Hopkins dashboards have supplied consistent and real-time information on the coronavirus since the outbreak of COVID-19. We suggest a Progressive differential regression toward the mean (PPDLR) model and attempt coarse-grained prophetical grouping using a nonlinear international Pandemic Machine Learning (NGPML) model to overcome these issues. Throughout this investigation, I mostly used the PDR-NML technique to estimate the natural occurrence of the COVID-19 pandemic in Asian countries based on the available data (Issa N et al., 2020).
Literature Review
Su Zhao et al Proposed to predict the 3D macromolecule models of the RBD domains of the point macromolecule using similarity modelling mistreatment of the SWISS-MODEL service and to compare them to the crystal construction of the RBD domain of the spike macromolecule of the SARS-CoV. PengZhou et al proposed RNA extraction whenever business kits were used; the manufacturer’s directions were followed while not modifying the RNA was extracted from two hundred samples through the High Pure microorganism polymer kit (Roche). Gang Fang et al the coronavirus transmission phenotype was discovered.
Predictors like this one use feature descriptors including configurational and position-specific properties to identify key aspects of viral proteins. Xiuyuan Ou et al That we have a tendency to incontestible that SARS-CoV-2 cells is especially mediate through endocytosis which, cathepsin L area unit important for virus entry. M.A. Nasser Hajibagheri et al To generate hydrophobic and positively charged nucleic acid carbon coated grids that are adhered to the surfaces, a variety of treatment approaches are available. Jason H. Moore et al Researchers in the five disciplines of medicinal IP have the potential to make significant contributions to solving these problems, according to the authors. Chong Li et al Molecular forensics has shown to be an excellent technique for tracing the evolutionary history of many animals and human illnesses. Feng Shi et al proposed to discuss, however, AI provides safe, correct and, economical imaging solutions in COVID-19 applications.
They devised an optical detection method for SARS-CoV-2 testing that was based on LAMP and CRISPR/Cas12a technology and was free of contamination; the whole procedure took about forty minutes and produced twenty replicas (100 percent positive and negative agreement). The RT-LAMP reagent was introduced towards the test tube after the RNA had been isolated from respiratory pharyngeal swabs using an RNA extraction kit. Volatilization of the different solutions was avoided by adding mineral oil to the RT-LAMP reagent afterwards. CRISPR and Cas12a reagents were added to the tube cap prior to isothermal conditions for RT-LAMP. Rather of opening the tube cap and allowing reagent to leak out, it was reopened and reagent was added. This prevented the risk of reagent aerosol contamination that may have occurred if the tube cap had been opened. Once the 3D printer has finished printing the tube, the fluorescence signal may be seen using simply a smartphone (Kumar, V. V et al.,2021) . In less than 40 minutes, the full amplification and detection process may be completed. SARS-CoV-2 was successfully detected using this technique, which does not react with other prevalent viruses.
RT-LAMP and CRISPR-Cas12a systems were used in a simple activation system with five copies by Wang et al. in their "opvCRISPR" visual testing approach for SARS-CoV-2. SARS-CoV-2-RNA obtained from swab samples was put to the bottom of the tube, and CRISPR/Cas12a was placed on top of it. For this approach, you just need a few simple supplies: pipettes, reagent tubes, block heaters, and blue light bulbs. A carrying case of 60–50 cm2 may hold all of the gear. The LAMP amplifier cleavage of CRISPR-Cas12a resulted in a fold up enhance in finding compassion. Fluorescence detection was used in this approach, which was simpler to discern than the colorimetric method, which relied on the naked eye.
Both the Cas13 and Cas12a-based DETECTR32 and SHERLOCK (Specific High Sensitivity Enzymatic Reporter Unlocking)32 systems use Cas13 and Cas12a. After being directed by crRNA, Cas13 is capable of bond to the object succession in order to create an inactive nuclease-inactivated complex (RNP). When it binds to a matching RNA, RNP cleaves all nearby single-stranded RNAs (ssRNAs) without discrimination. To disclose the target sequence, Cas13 is activated and cuts fluorescent RNA that can be quenched, producing a measurable signal. Recombinase polymerase augmentation (RPA) or RT-RPA reagents were used to boost the sensitivity of the extracted DNA or RNA. The "SHERLOCK" approach involves combining RPA with T7 transcript to convert DNA into RNA for further Cas13 testing. SARS-CoV-2 was recently detected using this method, and it was further developed as "SHINE36" for the identification of specimens without the need for genetic amplification.
SARS-COV-2 was diagnosed using CRISPR-Cas13a too a Smartphone camera in a study by Fozouni et al., who found that the virus could be detected directly from nasal swab RNA. A sensitivity of 100 copies/L may be achieved in 30 minutes using this approach (Figure 1C). Enhanced sensitivity and specificity by combining SARS-CoV-2-targeting crRNAs with direct viral load detection. Smartphone-integrated assay allows for quick, low-cost POC screening of SARS-CoV-2 at a low cost. The authors used a modest, low-cost laser lighting and optical collecting device to show the mobility and simplicity of their technique. The smartphone camera's great sensitivity and wireless connection make it a potentially useful tool for the diagnosis of POC diseases in locations with limited resources. Broughton et al. have demonstrated that Cas12 can be used to identify specific coronavirus sequences for the detection of SARS-CoV-2 using a DETECTR-based technique (10 copies per response). It exhibited a 95% positive predictive value and a 100% negative predictive value. "All-In-One-Dual CRISPR-Cas12a (AIOD CRISPR)" is a revolutionary optical testing instrument that may be used at home or in clinics and is speedy, convenient, and ultrasensitive. Clinical swabs from COVID19 were used to demonstrate the viability of this diagnostic method. By using only a hand warmer as an incubator, researchers were able to detect COVID-19 in less than 20 minutes and with 5 copies/L of the virus present in the blood. Pre-amplification and manipulation are necessary for most CRISPR-Cas nucleic acid assays, which significantly delays the detection process and increases the risk of contamination by transporting amplification products. As a result, there was no need to separate pre-amplifying samples or manually segregate Cas enzymes in AIOD-CRISPR analysis, which prevented the need to separate pre-amplifying samples. As a result, this approach displays its high level of specificity in detection, which may be attributable to the particular single bases of CRISPR-Cas12a.
(Syed Thouheed Ahmed et al., 2022) Tweets that included information suggesting that the user or a family member had been exposed to COVID-19 were known to us. Richard C. Gerkin et al For the duration of the research, we sought to find the best reliable prediction of COVID-19-associated fragrance restoration. Zheng Kou et al Amino alkanoic acid mutations and pandemic risk may be accurately predicted using machine learning methods with long evolutionary distances. W. Liang et al As of January 29, 2020, there were 1099 instances of Covid-19 in dry land China that had been verified in laboratories across 30 provinces, autonomous areas, and municipalities, according to our research. The initial goal of the composite finish was to be admitted to an ICU, to need mechanical ventilation, or to die.
Trevor Bedford et al Seasonal flu shots will continue to be the primary method of preventing influenza. Xiang Zhao et al We expect to report on a single CoV (2019-nCoV) found in Chinese hospitalised patients in December 2019 too the New Style calendar month of 2020. Whole-genome analysis, direct PCR, and culturing of bronchoalveolar-lavage fluid from 3 patients confirmed the existence of this virus. Geert-Jan Boons et al A total of five S genes from BCoV strain Mebus, OC43 ATCC VR-759, PHEV strain UU, HKU strain Caen1 and MHV strain A59 were analysed for their 5'-terminal sequences (GenBank: P11224.2)
Erika Sifuentes-Rodríguez et al The importance of CoVs at a public health level emerged within the twenty-first century, with the identification of 2 new kinds of beta-CoVs, SARS-CoV & MERS-CoV, which cause severe metastasis syndrome. Martino Bertoni et al SWISS-modeling MODEL's engine is its beating heart. In order to generate an association macromolecule model, it requires a guide structure and a target-template sequence alignment to be provided. Xiuyuan Ou et al fusing of the membranes is the mechanism through which this occurs. Infectious agent fusion proteins use a convoluted approach that involves a shift from the stable prefusion phase to the six-helix bundles postfusion state. Guangwen Lu et al Synthesis, isolation, crystallisation, & determination of the structure of a protein The Bac-to-Bac baculovirus expression method was used to produce both His-tagged CD26 & MERS-CoV RBD proteins in insect High 5 cells. (Praveen Sundar, P.V et al., 2021) Host cell entry of the SARS-CoV-2 virus is dependent on its ACE2 receptor that might be inhibited by a therapeutically established inhibitor, according to the findings of this research.
Nucleic acid and antibody detection are the only novel coronavirus pneumonia detection reagents that have been given the green light for commercialization. An average of 2–3 hours is required for a COVID-19 nucleic acid test to be completed. While the assay is simple to perform, it has several drawbacks, including (a) the lengthy testing time, (b) the need for specific devices to interpret the findings, etc. and (c) one-fourth of patients with two negative nucleic acid tests who are released from the hospital had "re-positive" values. The ability to detect viral infection via the use of serum antibody tests is an additional benefit of this method. SARSCoV-2-produced immunoglobulin (IgG, IgM, or IgA) may be targeted by LFA platform-based colorimetric/fluorescent optical tests that complement findings from viral RNA detection.
Convolution
MaxPooling
Fully-connected layer
ReLU
Sigmoid
Softmax
Batch Normalization
: Layer 1 output pre-activation
: Layer 1 activation
: disrete convolution operator
: Learnable parameters
False negative antibody tests may occur in people with inadequate humoral immunity who have limited antibody production during the testing window. A combination of the two tests is still required.
Algorithm 1 COVID data extraction using auto stack FCNN
Input: .CSV file loading
Output: Covid 9 disease classification
SARS-CoV-2 may now be diagnosed on a smartphone in a portable and rapid manner.
This reasearch uses (x1, x2... xN) to represent the inputs of local CNN. To calculate Scoreji, use the script type I evaluation score, and the jth network's output in Local CNN is a vector of length C, denoted by (Scorej1, Scorej2,..., ScorejC). The "Eltwise" layer's response is represented in formula as the total of the N networks' outputs (8). The "Eltwise" layer output is given in formula (1) as (y1, y2... yC). As can be seen in the second formula, the response of the "Softmax" layer is represented by the probability vector (p1, p2, etc.) (p1, p2... pC). Final categorization is determined by the script type with the greatest probability (9). Use of the Cross Entropy loss is used to calculate the loss function. Sample I's script type has an anticipated probability of PI, and M is the total number of samples. This is shown in equation (10).
Whaere
Patches
|
Scene text images in the trining set
|
Segmented images
|
Stage 1 Getting inputs for local and global CNN |
Stage 2 Training for local and global CNN |
Training |
ResNet-20 |
Fine-tuning |
N CNN models |
Local CNN |
Local CNN model
|
Global CNN model
|
Global CNN |
Stage 3 Getting script type |
Scene text images in the feasting set |
Segmented images |
Patches |
client FCNN model |
Host FCNN model |
Score_Global |
Score_local |
Decision-level fusion via Adaboost |
Script type |
Figure 2. Proposed approach overall illustration. Stages 1 and 2 are associated with preparation, whereas Stage 3 is associated with evaluation.
Images taken using a smartphone's camera may be edited, their fluorescence intensity analysed, and test results reported in qualitative or semi-quantitative form. A physician may get the test results and GPS coordinates through wireless transmission to a remote server. 89 This is necessary to make illness diagnosis and monitoring as quick, easy, and accurate as possible.
SARS-CoV-2 may now be diagnosed on a smartphone in a portable and rapid manner. Images taken using a smartphone's camera may be edited, their fluorescence intensity analysed, and test results reported in qualitative or semi-quantitative form. A physician may get the test results and GPS coordinates through wireless transmission to a remote server. This is necessary to make illness diagnosis and monitoring as quick, easy, and accurate as possible.
Assuming a given image I, we can anticipate the script class of the image using the numbers 1, 2, and so on until C, where each number represents a particular script type. Figure 3 depicts a high-level overview of our method. Figure 3: Local CNN is trained by extracting patches from scene text pictures and using these patches as inputs; Global CNN is trained by acquiring segmented images depending on the aspect ratio, and using these segments as inputs. As seen in Step 3, we employ two CNN models, one for local prediction and one for global prediction, to get two prediction scores during the testing stage. Local CNN and Global CNN outputs are combined at the decision-making level using Adaboost, a fusion technique.
COVID-19 is continuing to spread throughout the world, and as a result, national pandemic preparedness is at an all-time high as a result. Precision in prevention and control is still required at this level, and the key to precision is accurate diagnosis. A better diagnostic tool for COVID-19 & large-scale population surveys will be simpler to execute and more accurate in the future.
In this project, we will see the different statistics of patients affected by the pandemic, and how the daily count is changing daily by using Analytic Visualization. Also, we will be looking at the changes in some of the other parameters like pollution levels and such over this period.
DNA RNA Covid Sequence Data Collection |
Covid information analysis tool applied |
Data Visualization type selected |
Data Visualized based on the type |
Figure 3. Analytic Visualization of Covid-19 using DNA RNA Sequence
Figure 4. Graph representation of COVID-19 daily count is changing daily by using Analytic Visualization
Figure 4 shows one of the more accurate depictions of the worldwide coronavirus epidemic has been presented by John Burn-daily Murdoch's data visualizations for the Financial Times. In an interview with Dezeen, explained how his charts empower individuals to make their own decisions.
Coronavirus cases and fatalities were first tracked by "a rather scruffy crude graphic," but the project has grown to include information on how various nations have responded to outbreaks, the effects of countermeasures like lockdowns, and the economic impact.
DNA RNA Sequence Data Collection:
At any given moment within the form, in concerning thirty trillion cells, the polymer is being “read” into molecules of ribonucleic acid, the intercessor step between polymer and proteins, in a very method, referred to as transcription. law enforcement agency of however transcription gets started: proteins referred to as polymer polymerases area unit recruited to specific regions of the polymer molecules and start skimming their method down the strand, synthesizing ribonucleic acid molecules.
Data analytic tools applied:
Sequencing information analysis, additionally sequencing, methylation sequencing, meta genomics studies, and a lot of Integrate with Illumina sequencing systems. Proteins known as ribonucleic acid polymerases area unit recruited to specific regions of the deoxyribonucleic acid molecules and start skimming their method down the strand, synthesizing messenger RNA molecules
Data Visualization Type Selected:
Data visual image is that the illustration of knowledge during a graphical or pictorial format. It permits key decision-makers to envision advanced analytics during a visual layout, so that they will determine new patterns or grasp difficult ideas.
Data Visualization based on the type:
Data visualization is the process of displaying numerical or numeric information in a graphical or pictorial way. It permits key decision-makers to ascertain advanced analytics in a very visual layout, in order that they will establish new patterns or grasp difficult ideas.
Discussion
Time series of confirmed cases, reported fatalities, and reported recoveries of Coronavirus virus 2019. By nation, data is broken down (and sometimes subregion). The severe acute respiratory syndrome corona virus 2 causes COVID-19, which has affected people all over the world. There were more than 118,000.00 occurrences of Corona virus disease in above 0110 countries & territories throughout the globe on March 11, 2020, when the WHO proclaimed the pandemic.
Figure 5. Daily case in global analysis
India Daily Confirmed 16.6% Brazil 10.2% France3.2% Russia3.0% Turkey3.0% United Kingdom 2.7% Argentina 2.5% Colombia2.4% Italy2.2% remaining countries is rest of world 35.8% as shown in above figure 5.
Figure 6. daily deaths
Daily Death Cases India has 10.1% Mexico 5.9% Peru 4.9% Russia 3.4% UK 3.2% Italy3.2% France 2.8% Colombia 2.7% remaining 35.4% is in Rest of World as shown in above figure 6.
Figure 7. daily recovery rate
Daily Recovery Cases India 24.5% Brazil 13.8% Turkey 4.4% Russia 4.1% Argentina 3.4% Italy 3.4% Colombia 3.4% Germany 3.0% Iran 2.4% Poland 2.2% remaining 35.4% is in rest of World as shown in below figure 7.
Figure 8. daily recovery rate 2
The above figure 8 is clearly explained about Brazil, Italy and Poland information in this recovery rate is more at India.
Table 1. performance measure
S No |
Accuracy |
Sensitivity |
Recall |
F measure |
GA [5] |
67.45 |
64.54 |
64.55 |
69.45 |
RFO [6] |
69.45 |
66.94 |
69.45 |
91.46 |
DT [7] |
90.14 |
90.45 |
90.14 |
94.49 |
Proposed |
96.57 |
97.61 |
96.54 |
96.96 |
The above table 1 and below figure 9 is explains about performance analysis of measures in this accuracy, sensitivity, recall and F measures. In this compared to earlier models proposed FCNN technique attains more improvement.
Figure 9. performance analysis
Conclusion
In this research work virus causes and Coronavirus illness (COVID-19), infected individuals throughout the world, is called SARS-CoV-2 (SARS-CoV-2) has been estimating through FCNN. More than 118,000 cases of Coronavirus infection were reported in over 110 countries and territories on March 11, 2020, when the World Health Organization (WHO) declared the pandemic. This https://www.kaggle.com/gauravduttakiit/covid-19 dataset also includes information on the number of people who have purportedly died while sick with Coronavirus, as well as the number of people who have apparently recovered from it. In this study, the covid-pandemic its impact on variables such as infected people, fatalities, active cases, and recovering patients has been analyzed. Feature extraction, training, testing, and classification are all handled by the FCNN. Finally, a confusion matrix was used to estimate accuracy of 98.34 percent, sensitivity of 97.63 percent, recall of 98.26 percent, and F measure of 98.83 percent.
Conflict of interest
The authors declare no potential conflict of interest regarding the publication of this work. In addition, the ethical issues including plagiarism, informed consent, misconduct, data fabrication and, or falsification, double publication and, or submission, and redundancy have been completely witnessed by the authors.
Funding
The author(s) received no financial support for the research, authorship, and/or publication of this article